R. Schoeman, K. Mathwig, European Patent Application EP4282340A1; United States Patent Application US20230380816A1. [link, pdf]

An ingestible device for sampling material at least one time is provided. The ingestible device comprises a first chamber being enlargeable in space, comprising an inlet, and to be filled with the material to be sampled, a second chamber being diminishable in space, comprising an outlet, and a reversible actuating mechanism. In this context, the reversible actuating mechanism is configured such that triggering the reversible actuating mechanism leads to an enlargement of the first chamber to collect the material to be sampled through the inlet and to a diminishment of the second chamber.